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Corning® Gentest™转运体膜阴性对照:Corning® Gentest™ Negative Control Membranes 0.5ml

价格:¥

货号:453200
品牌:Gentest

经销:基因有限公司

含重组ABC(ATP-bindingcasette transporter)转运蛋白的阴性对照,5mg/ml,0.5ml。操作简便,高通量,适用于非放射性标记的ABC蛋白底物分析,或检测药物刺激的钒酸酯敏感性ATP酶活性 This preparation should be used as a negative control with recombinant ABC transporters, e.g. human P-gp (MDR1) membranes. Protein concentration: 5 mg/ml. 0.5ml

Gentest™ 肝细胞转运蛋白分析试剂盒/Gentest™ Hepatocyte Transporter Suspension Assay Kit 1 Unit

价格:¥

货号:454460
品牌:Gentest

经销:基因有限公司

肝细胞转运蛋白分析试剂盒,含有抑制转运蛋白膜活性成分,100tests,包含操作说明书、10ml滤油,100个离心管。储存过程中可能会出现分层现象,可通过低速轻甩混匀后重新使用。 This kit provides a detailed protocol for hepatocyte transporter uptake assays. It contains the critical components for stopping transport activity and separating hepatocytes from the uptake solution for 100 assay data points. This kit is a convenient in vitro method for measuring transporter activity in cryopreserved or fresh hepatocyte suspensions (Current Drug Metabolism 8:341 [2007]). The filtration assay depends on an oil layer or “cushion” which serves as a barrier between the reaction mix (hepatocytes and substrate) and a lower layer of 2N NaOH. After the incubation period, the assay mixture (containing cells, substrate, and buffer) is layered on top of the oil cushion and centrifuged briefly. The hepatocytes pass through the filtration oil into the lower layer of NaOH, which serves to solubilize the cell membrane and release the radiolabeled substrate.
The oil layer barrier prevents the aqueous assay mix containing free radiolabeled substrate from entering the NaOH layer.The lower portion of the microcentrifuge tube, containing the cells and transported substrate, is cut away from the upper layer, mixed with scintillation cocktail, and measured by scintillation counting. The assay is carried out at both 4°C and 37°C; the 4°C sample serves as the negative control (disintegrations per minute [DPM] at 4°C represents nonspecific binding).

Corning® Gentest™大鼠 P-gp (Mdr1a) 转运体膜:Corning® Gentest™ Rat P-gp (Mdr1a) Membranes 0.5ml

价格:¥

货号:453440
品牌:Gentest

经销:基因有限公司

含大鼠P-糖蛋白结合的ABC家族Mdr1b蛋白的人工膜,一种ATP依赖的物质转运泵,在肠道、大脑、肝脏等组织中内源表达,可实现跨膜转运药物的功能,可作为肿瘤化学药物治疗效果的指标,5mg/ml,0.5ml。操作简便,高通量,适用于非放射性标记的ABC蛋白底物分析,或检测药物刺激的钒酸酯敏感性ATP酶活性 Rat Mdr1a is an ATP-dependent efflux pump capable of transporting many drugs across cell membranes. It is expressed in the intestine, brain, liver, and other tissues. 0.5mL, 5mg/mL.
This product is prepared from baculovirus infected insect cells. A method to perform a colorimetric ATPase assay in 96-well plates is provided in the batch data sheet. Other applications of this product are possible. Representative verapamil-stimulated vanadate-sensitive ATPase activity: xx* nmol phosphate/(mg membrane protein)(min). Protein concentration: 5 mg/ml. Package size: 0.5 ml.

Corning® Gentest™ 小鼠 P-gp (Mdr1b) 转运体膜:Corning® Gentest™ Mouse P-gp (Mdr1b) Membrane 0.5ml

价格:¥

货号:453250
品牌:Gentest

经销:基因有限公司

含小鼠ABC蛋白超家族Mdr1b蛋白的人工膜,一种ATP依赖的物质转运泵,可实现跨膜转运药物的功能,在小肠、大脑、肝脏等组织中内源表达,可作为肿瘤化学药物治疗效果的动物实验指标,5mg/ml,0.5ml。操作简便,高通量,适用于非放射性标记的ABC蛋白底物分析,或检测药物刺激的钒酸酯敏感性ATP酶活性。 Mouse Mdr1b is an ATP-dependent efflux pump capable of transporting many drugs across cell membranes. It is expressed in the intestine, liver, and other tissues. 0.5mL, 5mg/mL.
This product is prepared from baculovirus-infected insect cells. A method to perform a colorimetric ATPase assay in 96-well plates is provided in the batch data sheet. Other applications of this product are possible. Representative verapamil-stimulated vanadate-sensitive ATPase activity: xx* nmol phosphate/(mg membrane protein)(min). Protein concentration: 5 mg/ml. Package size: 0.5 ml.

Corning® Gentest™人P-gp (MDR1)转运体膜:Corning® Gentest™ Human P-gp (MDR1) Membranes 0.5ml

价格:¥

货号:453228
品牌:Gentest

经销:基因有限公司

含人P-糖蛋白结合的ABC家族MDR1蛋白的人工膜,一种ATP依赖的物质转运泵,可实现跨膜转运药物的功能,可作为肿瘤化学药物治疗效果的指标,5mg/ml,0.5ml。操作简便,高通量,适用于非放射性标记的ABC蛋白底物分析,或检测药物刺激的钒酸酯敏感性ATP酶活性 Human P-gp (MDR1) is an ATP-dependent efflux pump that is capable of transporting many drugs across cell membranes. High level expression of this protein has been linked to tumor resistance to chemotherapy. 0.5mL, 5mg/mL.
This product is prepared from baculovirus-infected insect cells. A method to perform a colorimetric ATPase assay in 96-well plates is provided in the batch data sheet. Other applications of this product are possible. Representative verapamil-stimulated, vanadate-sensitive ATPase activity: 32 nmol phosphate/(mg membrane protein)(min).

Corning® Gentest™小鼠 P-gp (Mdr1a) 转运体膜:Corning® Gentest™ Mouse P-gp (Mdr1a) Membrane 0.5ml

价格:¥

货号:453232
品牌:Gentest

经销:基因有限公司

含小鼠ABC蛋白超家族Mdr1a蛋白膜的人工膜,一种ATP依赖的物质转运泵,可实现跨膜转运药物的功能,在小肠、大脑、肝脏等组织中内源表达,可作为肿瘤化学药物治疗效果的动物实验指标,5mg/ml,0.5ml。操作简便,高通量,适用于非放射性标记的ABC蛋白底物分析,或检测药物刺激的钒酸酯敏感性ATP酶活性。 Mouse MDR1a is an ATP-dependent efflux pump capable of transporting many drugs across cell membranes. It is expressed in the intestine, brain, liver, and other tissues. 0.5mL, 5mg/mL.
This product is prepared from baculovirus-infected insect cells. A method to perform a colorimetric ATPase assay in 96-well plates is provided in the batch data sheet. Other applications of this product are possible. Representative verapamil-stimulated vanadate-sensitive ATPase activity: 14 nmol phosphate/(mg membrane protein)(min). Protien concentration: 5 mg/ml. Package size: 0.5 ml.

Corning® Gentest™大鼠 P-gp (Mdr1b) 转运体膜:Corning® Gentest™ Rat P-gp (Mdr1b) Membranes 0.5ml

价格:¥

货号:453434
品牌:Gentest

经销:基因有限公司

含大鼠P-糖蛋白结合的ABC家族Mdr1b蛋白的人工膜,一种ATP依赖的物质转运泵,在肠道、肝脏等组织中内源表达,可实现跨膜转运药物的功能,可作为肿瘤化学药物治疗效果的指标,5mg/ml,0.5ml。操作简便,高通量,适用于非放射性标记的ABC蛋白底物分析,或检测药物刺激的钒酸酯敏感性ATP酶活性 Rat MDR1b is an ATP-dependent efflux pump capable of transporting many drugs across cell membranes. It is expressed in the intestine, liver, and other tissues. 0.5mL, 5mg/mL.
This product is prepared from baculovirus-infected insect cells. A method to perform a colorimetric ATPase assay in 96-well plates is provided in the batch data sheet. Other applications of this product are possible. Representative verapamil-stimulated vanadate-sensitive ATPase activity: 7 nmol phosphate/(mg membrane protein)(min). Protien concentration: 5 mg/ml. Package size: 0.5 ml.

Corning® Gentest™大鼠 Bcrp 转运体膜:Corning® Gentest™ Rat Bcrp Membranes 0.5ml

价格:¥

货号:453457
品牌:Gentest

经销:基因有限公司

大鼠BRCP膜,5mg/ml,0.5ml。操作简便,高通量,适用于非放射性标记的ABC蛋白底物分析,或检测药物刺激的钒酸酯敏感性ATP酶活性。 BCRP (MXR/ABCG2) is a member of ABC superfamily that expresses in many tissues, such as brain, placenta, liver, and intestine. BCRP plays important roles in protecting those tissues against toxic compounds, drugs, and drug metabolites. Rat BCRP was cloned from rat liver cDNA library. 0.5mL, 5mg/mL.
This product was prepared using baculovirus infected insect cells expression system. A method to perform a colorimetric ATPase assay in 96 well plates is provided in the batch data sheet. Other applications of this product are possible. Representative PhIP-stimulated vanadate-sensitive ATPase activity: 33 nmol phosphate/(mg membrane protein)(min).

Corning® Gentest™人MRP3 转运体膜:Corning® Gentest™ Human MRP3 Membranes 0.5ml

价格:¥

货号:453333
品牌:Gentest

经销:基因有限公司

含人ABC蛋白超家族成员MRP3蛋白的人工膜,在肝脏、肾上腺、小肠等组织中内源表达,参与有机阴离子盐、有机阴离子偶联化合物和其他ATPase底物的转运,可作为肿瘤化学药物治疗效果的指标,5mg/ml,0.5ml。操作简便,高通量,适用于非放射性标记的ABC蛋白底物分析,或检测药物刺激的钒酸酯敏感性ATP酶活性 Human MRP3 is an ATP-dependent efflux pump belonging to the ABC transporter superfamily. It is expressed in liver, adrenal glands, kidney, small intestine, and other tissues. Human MRP3 is capable of transporting many organic anions, organic anion conjugates, and other substrates across cell membranes. High level expression of this protein has been linked to drug resistance during chemotherapy. 0.5mL, 5mg/mL.
This product is prepared from baculovirus infected insect cells. A method to perform a colorimetric ATPase assay in 96 well plates is provided in the batch data sheet. Other applications of this product are possible. Representative Benzbromarone-stimulated vanadate-sensitive ATPase activity: 10.8 nmol phosphate/(mg membrane protein)(min).

Corning® Gentest™ 人 MRP1 转运体膜:Corning® Gentest™ Human MRP1 Membranes 0.5ml

价格:¥

货号:453456
品牌:Gentest

经销:基因有限公司

含人ABC蛋白超家族成员MRP1蛋白的人工膜,在肺、睾丸、骨骼肌等组织中内源表达,参与有机阴离子盐、有机阴离子偶联化合物和其他ATPase底物的转运,可作为肿瘤化学药物治疗效果的指标,5mg/ml,0.5ml。操作简便,高通量,适用于非放射性标记的ABC蛋白底物分析,或检测药物刺激的钒酸酯敏感性ATP酶活性 Human MRP1 (ABCC1) is an ATP-dependent efflux pump belonging to the ABC transporter superfamily. It is expressed in lung, testis, skeletal muscle, and other tissues. Human MRP1 is capable of transporting many organic anions, organic anion conjugates and other substrates across cell membranes. High level expression of this protein has been linked to drug resistance during chemotherapy. 0.5mL, 5mg/mL.
This product is prepared from baculovirus infected insect cells. A method to perform a colorimetric ATPase assay in 96 well plates is provided in the batch data sheet. Other applications of this product are possible. Representative NEM-stimulated vanadate-sensitive ATPase activity: xx nmol phosphate/(mg membrane protein)(min).

Gentest™ BSEP Vesicle Assay Kit Gentest™ BSEP囊泡分析试剂盒 1 Unit

价格:¥

货号:459011
品牌:Gentest

经销:基因有限公司

BSEP囊泡分析试剂盒,200 tests This assay kit characterizes the substrates or inhibitors of Bile Salt Export Pump (BSEP). The assay measures the cumulative uptake of test compounds in the inside-out BSEP vesicle transporter to directly identify BSEP substrates or inhibitors.

Shelf Life:2 years
Shipping:Dry ice
Features
• Supports EMA recommended BSEP
• Provides one simple protocol to accommodate both Corning human and animal BSEP vesicle studies
• Supports high-volume cell harvester applications with bulk wash buffers available separately
• Saves researchers time by eliminating reagent preparation steps; assays can be completed within one day
• Supports multiple time usage with robust, stable reagents accommodating up to six freeze-thaw cycles

Contents
Kit contains reagents for 200 assays
• Assay Uptake Buffer
• 10 X Wash Buffer
• 200 mM ATP
• 200 mM AMP
• BSEP Substrate
• Blocking Buffer (50X)

Preparation and Storage: -20°C

Corning® Gentest™人MRP2 转运体膜:Corning® Gentest™ Human MRP2 Membranes 0.5ml

价格:¥

货号:453332
品牌:Gentest

经销:基因有限公司

含人ABC蛋白超家族成员MRP2蛋白的人工膜,在肝脏、肾脏、大脑等组织中内源表达,参与有机阴离子盐、有机阴离子偶联化合物和其他ATPase底物的跨膜转运,可作为肿瘤化学药物治疗效果的指标,5mg/ml,0.5ml。操作简便,高通量,适用于非放射性标记的ABC蛋白底物分析,或检测药物刺激的钒酸酯敏感性ATP酶活性。 Human MRP2 an ATP-dependent efflux pump belonging to the ABC transporter superfamily. It is expressed in liver, kidney, brain, and other tissues. Human MRP2 is capable of transporting many organic anions, organic anion conjugates, and other substrates across cell membranes. High level expression of this protein has been linked to drug resistance during chemotherapy. 0.5mL, 5mg/mL.
This product is prepared from baculovirus infected insect cells. A method to perform a colorimetric ATPase assay in 96 well plates is provided in the batch data sheet. Other applications of this product are possible. Representative probenecid-stimulated vanadate-sensitive ATPase activity: xx nmol phosphate/(mg membrane protein)(min).

Corning® Gentest™小鼠 Bcrp 转运体膜:Corning® Gentest™ Mouse Bcrp Membranes 0.5ml

价格:¥

货号:453251
品牌:Gentest

经销:基因有限公司

小鼠BCRP膜,5mg/ml,0.5ml。操作简便,高通量,适用于非放射性标记的ABC蛋白底物分析,或检测药物刺激的钒酸酯敏感性ATP酶活性。 BCRP (MXR/ABCG2) is a member of the ABC superfamily. It expresses in many tissues, such as brain, placenta, liver, and intestine. BCRP plays important roles in protecting those tissues against toxic compounds, drugs, and drug metabolites. Mouse BCRP was cloned from mouse liver cDNA library. 0.5mL, 5mg/mL.
This product was prepared using baculovirus infected insect cells expression system. A method to perform a colorimetric ATPase assay in 96 well plates is provided in the batch data sheet. Other applications of this product are possible. Representative Sulfasalazine-stimulated vanadate-sensitive ATPase activity: XX nmol phosphate/(mg membrane protein)(min).

Corning® Gentest™转运囊泡阴性对照:Corning® Gentest™ Negative Control Vesicles 0.5ml

价格:¥

货号:453500
品牌:Gentest

经销:基因有限公司

含ABC(ATP-bindingcasette transporter)转运蛋白的控制囊泡,一种重组形式提供的蛋白控制囊泡,阴性对照,5mg/ml,0.5ml。操作简便,可用于放射性元素标记或未标记化合物的摄取分析。 This preparation should be used as a negative control with recombinant ABC transporter vesicles. E.g.: human MRP2 Vesicles (Cat. No. 453450). Representative LTC4 Uptake Activity: 2.6 pmole/min/mg in the presence of ATP; 1.2 pmol/min/mg in the absence of ATP. 0.5mL, 5mg/mL.

Corning® Gentest™ 大鼠 Mrp1 转运囊泡:Corning® Gentest™ Rat Mrp1 Vesicles 0.5ml

价格:¥

货号:453510
品牌:Gentest

经销:基因有限公司

含大鼠ABC蛋白超家族MRP1蛋白的囊泡,在肝脏、肾脏、大脑等组织中内源表达,参与有机阴离子盐、有机阴离子偶联化合物和其他ATPase底物的转运,可作为肿瘤化学药物治疗效果的指标,5mg/ml,0.5ml。操作简便,可用于放射性元素标记或未标记药物化合物的摄取分析,适用于高通量分析。 Rat MRP1 (ABCC1) is an ATP-dependent efflux pump, belonging to the ABC transporter superfamily. It is expressed in liver, kidney, brain, and other tissues. Rat MRP1 is capable of transporting many organic anions, organic anion conjugates, and other substrates across cell membranes. High level expression of this protein has been linked to drug resistance during chemotherapy. 0.5mL, 5mg/mL.
This product is prepared from baculovirus infected insect cells. A method to perform an uptake assay with and without ATP using radiolabeled substrates in 96-well plates is provided in the batch data sheet. Other applications of this product are possible. Representative LTC4 Uptake Activity: 78 pmole/min/mg in the presence of ATP; 14 pmole/min/mg in the absence of ATP.

Corning® Gentest™ 大鼠 Bsep 转运囊泡:Corning® Gentest™ Rat Bsep Vesicles 0.5ml

价格:¥

货号:453501
品牌:Gentest

经销:基因有限公司

大鼠BSEP囊泡,5mg/ml,0.5ml。操作简便,可用于放射性元素标记或未标记药物化合物的摄取分析,适用于高通量分析。 Rat BSEP is an ATP-dependent efflux pump belonging to the ABC transporter superfamily. Expressed in liver, RAT SEP is capable of transporting bile salts, some organic anions, and organic anion conjugates across hepatic canalicular membrane. 0.5mL, 5mg/mL. This product is prepared from baculovirus infected insect cells. A method to perform an uptake assay with and without ATP using radiolabeled substrates in 96-well plates is provided in the batch data sheet. Other applications of this product are possible. Representative TCA Uptake Activity: 3.2 pmole/min/mg in the presence of ATP; 1.3 pmole/min/mg in the absence of ATP.

Corning® Gentest™ 人 MRP1 转运囊泡:Corning® Gentest™ Human MRP1 Vesicles 0.5ml

价格:¥

货号:453455
品牌:Gentest

经销:基因有限公司

含人P-糖蛋白结合的ABC家族MRP1蛋白的囊泡,5mg/ml,0.5ml。操作简便,可用于放射性元素标记或未标记药物化合物的摄取分析,适用于高通量分析。 Human MRP1 (ABCC1) is an ATP-dependent efflux pump belonging to the ABC transporter superfamily. It is expressed in lung, testis, skeletal muscle, and other tissues. Human MRP1 is capable of transporting many organic anions, organic anion conjugates, and other substrates across cell membranes. High level expression of this protein has been linked to drug resistance during chemotherapy. 0.5mL, 5mg/mL.
This product is prepared from baculovirus infected insect cells. A method to perform an uptake assay with and without ATP using radiolabeled substrates in 96-well plates is provided in the batch data sheet. Other applications of this product are possible. Representative LTC4 Uptake Activity: 70 pmole/min/mg in the presence of ATP; 13 pmole/min/mg in the absence of ATP.

Corning® Gentest™ 人 MRP2 转运囊泡:Corning® Gentest™ Human MRP2 Vesicles 0.5ml

价格:¥

货号:453450
品牌:Gentest

经销:基因有限公司

含人P-糖蛋白结合的ABC家族MRP2蛋白的囊泡,5mg/ml,0.5ml。操作简便,可用于放射性元素标记或未标记药物化合物的摄取分析,适用于高通量分析。 Human MRP2 (ABCC2) is an ATP-dependent efflux pump belonging to the ABC transporter superfamily. It is expressed in liver, kidney, brain, and other tissues. Human MRP2 is capable of transporting many organic anions, organic anion conjugates, and other substrates across cell membranes. High level expression of this protein has been linked to drug resistance during chemotherapy. 0.5mL, 5mg/mL.
This product is prepared from baculovirus infected insect cells. A method to perform an uptake assay with and without ATP using radiolabeled substrates in 96-well plates is provided in the batch data sheet. Other applications of this product are possible. Representative LTC4 Uptake Activity: 7.4 pmole/min/mg in the presence of ATP; 0.9 pmole/min/mg in the absence of ATP.

Corning® Gentest™人 MRP3 转运囊泡:Corning® Gentest™ Human MRP3 Vesicles 0.5ml

价格:¥

货号:453520
品牌:Gentest

经销:基因有限公司

含人P-糖蛋白结合的ABC家族MRP3蛋白的囊泡,5mg/ml,0.5ml。操作简便,可用于放射性元素标记或未标记药物化合物的摄取分析,适用于高通量分析。 Human MRP3 (ABCC3) is an ATP-dependent efflux pump belonging to the ABC transporter superfamily. It is expressed in adrenal glands, kidney, small intestine, and other tissues. Human MRP3 is capable of transporting many organic anions, organic anion conjugates, and other substrates across cell membranes. High level expression of this protein has been linked to drug resistance during chemotherapy. 0.5mL, 5mg/mL 。 This product is prepared from baculovirus infected insect cells. A method to perform an uptake assay with and without ATP using radiolabeled substrates in 96-well plates is provided in the batch data sheet. Other applications of this product are possible. Representative E217bG Uptake Activity: 2.2 pmole/min/mg in the presence of ATP; 0.5 pmole/min/mg in the absence of ATP.

Corning® Gentest™大鼠 Mrp2 转运囊泡:Corning® Gentest™ Rat Mrp2 Vesicles 0.5ml

价格:¥

货号:453523
品牌:Gentest

经销:基因有限公司

含大鼠ABC蛋白超家族MRP2蛋白的囊泡,在肝脏、肾脏、大脑等组织中内源表达,参与有机阴离子盐、有机阴离子偶联化合物和其他ATPase底物的转运,可作为肿瘤化学药物治疗效果的指标,5mg/ml,0.5ml。操作简便,可用于放射性元素标记或未标记药物化合物的摄取分析,适用于高通量分析。 Rat MRP2 (ABCC2) is an ATP-dependent efflux pump belonging to the ABC transporter superfamily. It is expressed in liver, kidney, brain, and other tissues. Rat MRP2 is capable of transporting many organic anions, organic anion conjugates, and other substrates across cell membranes. High level expression of this protein has been linked to drug resistance during chemotherapy. 0.5mL, 5mg/mL This product is prepared from baculovirus infected insect cells. A method to perform an uptake assay with and without ATP using radiolabeled substrates in 96-well plates is provided in the batch data sheet. Other applications of this product are possible. Representative LTC4 Uptake Activity: X.X pmole/min/mg in the presence of ATP; X.X pmole/min/mg in the absence of ATP.

Corning® Gentest™人 BSEP 转运囊泡:Corning® Gentest™ Human BSEP Vesicles 0.5ml

价格:¥

货号:453502
品牌:Gentest

经销:基因有限公司

人BSEP囊泡模型,5mg/ml,0.5ml。操作简便,可用于放射性元素标记或未标记药物化合物的摄取分析,适用于高通量分析。 Human BSEP Vesicles, 0.5mL, 5mg/mL

Corning® Gentest™人 BCRP (Arg482) 转运体膜:Corning® Gentest™ Human BCRP (Arg482) Membran 0.5ml

价格:¥

货号:453270
品牌:Gentest

经销:基因有限公司

人BCRP (Arg482)膜模型,5mg/ml,0.5ml。操作简便,高通量,适用于非放射性标记的ABC蛋白底物分析,或检测药物刺激的钒酸酯敏感性ATP酶活性 Human BCRP (Arg482) Membranes, 0.5mL, 5mg/mL

Corning® Gentest™人 BCRP (Thr482) 转运体膜:Corning® Gentest™ Human BCRP (Thr482) Membran 0.5ml

价格:¥

货号:453257
品牌:Gentest

经销:基因有限公司

人 BCRP (Thr482) 膜,5mg/ml,0.5ml。操作简便,高通量,适用于非放射性标记的ABC蛋白底物分析,或检测药物刺激的钒酸酯敏感性ATP酶活性 Human BCRP (Thr482) Membranes, 0.5mL, 5mg/mL

Gentest™ MRP/BCRP Vesicle Assay KitGentest™ MRP/BCRP 囊泡分析试剂盒 1 Unit

价格:¥

货号:459010
品牌:Gentest

经销:基因有限公司

MRP/BCRP 囊泡分析试剂盒,200 tests MRP/BCRP Vesicle Assay Kit for characterizing the substrates or inhibitors of MRP/BCRP transporters. The assay measures the cumulative uptake of test compounds in the inside-out MRP or BCRP vesicle transporters to directly determine the substrates or inhibitors of ABC transporters. This is done using radioisotope-labeled compounds or fluorescence compounds. The kit provides reagents for 200 assays and accommodates 4 vials of vesicles.

Features
• Supports FDA-recommended BCRP, as well as MRP vesicle panel.
• Provides one simple protocol to accommodate Corning human and animal MRP/BCRP vesicle studies.
• Delivers maximum flexibility allowing researchers the ability to perform a single transporter study or both MRP and BCRP studies with one kit.
• Supports high-volume cell harvester applications with bulk wash buffers available separately.
• Provides researchers an alternative to radiolabeled compounds with included CDCF fluorescent substrate for MRP2/MRP3 transporters.
• Saves researchers time by eliminating reagent preparation steps; assays can be completed within one day.
• Supports multiple time usage with robust, stable reagents accommodating up to six freeze-thaw cycles.

Contents
Kit contains reagents for 200 assays
• Assay Uptake Buffer
• 10X Wash Buffer
• 200 mM ATP
• 200 mM AMP
• 300 mM GSH
• MPR3 Substrate
• BCRP Substrate
• MRP2/MPR3 Fluorescent Substrate
• MRP1/MRP2 Substrate

Preparation and Storage:-80°C
Shelf Life:2 years
Shipping:Dry ice

Corning® Gentest™大鼠 Bcrp 转运囊泡:Corning® Gentest™ Rat Bcrp Vesicles 0.5ml

价格:¥

货号:453345
品牌:Gentest

经销:基因有限公司

含大鼠BCRP蛋白的囊泡,5mg/ml,0.5ml。操作简便,可用于放射性元素标记或未标记药物化合物的摄取分析,适用于高通量分析。 Rat BCRP Vesicles, 0.5mL, 5mg/mL

Corning® Gentest™人 BCRP (Arg482) 转运囊泡:Corning® Gentest™ Human BCRP (Arg482) Vesicle 0.5ml

价格:¥

货号:453271
品牌:Gentest

经销:基因有限公司

人BCRP (Arg482)囊泡模型,5mg/ml,0.5ml。操作简便,可用于放射性元素标记或未标记药物化合物的摄取分析,适用于高通量分析。 Human BCRP (Arg482) Vesicles, 0.5mL, 5mg/mL

Corning® Gentest™小鼠Bcrp转运囊泡:Corning® Gentest™ Mouse Bcrp Vesicles 0.5ml

价格:¥

货号:453252
品牌:Gentest

经销:基因有限公司

小鼠BCRP囊泡,5mg/ml,0.5ml。操作简便,高通量,适用于非放射性标记的ABC蛋白底物分析,或检测药物刺激的钒酸酯敏感性ATP酶活性。 Mouse BCRP Vesicles, 0.5mL, 5mg/mL

Corning® ATP酶分析试剂盒/Corning® ATPase Assay Kit 1 Unit

价格:¥

货号:459006
品牌:Gentest

经销:基因有限公司

ATP酶分析试剂盒,5*96 次反应。比色分析法,可通过检测释放的无机盐磷的含量快速检测ABC转运蛋白状态。保质期:2年。 This colorimetric ATPase assay kit rapidly screens ABC transporter proteins (membranes) for potential substrates or inhibitors. The assay determines ATPase activity by measuring the release of inorganic phosphate resulting from substrate-stimulated ATP.

Shelf Life:2 years. Quality: Validated using P-gp, MRP1, MRP2, MRP3 and BCRP membrane

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